Plné znění - 74/2013 Sb.

Xx. I

Vyhláška č. 474/2002 Sb., xxxxxx xx xxxxxxx xxxxx x. 281/2002 Xx., x některých xxxxxxxxxx souvisejících xx xxxxxxx xxxxxxxxxxxxxxxxx (xxxxxxxxxxxx) x toxinových xxxxxx x o xxxxx xxxxxxxxxxxxxx xxxxxx, xx xxxx xxxxx:

1. X §3 písmeno x) xxx:

"x) v oblastech xxxxxxxxxxx xxx x xxxxxxxxxxx nebo xxxxxxxxxx xxx ve studijních xxxxxxx, které xx xxxxxx xxxxxxxxx s xxxxxxxxxxxx xxxxx a xxxxxx,".

2. V §3 xxxx. c) se xx xxxxx "farmacie" xxxxxxxx slova "xxxx xxxxxxxxxxx".

3. V §3 xxxx. x) xx xx xxxxx "xxxxxxxxxxxxxxxxx" xxxxxxxx xxxxx "xxxx xxxxxxxxxxx" a slovo "xxxx" se xxxxxxxxx xxxxxx "xxxxxx".

4. X §4 xxxx první xx xxxxx "xxxxxx xxxxxxxxxxx" xxxxxxxxx xxxxx "xxxxxx xxxxx", xxxxx "xxxxx" xx xxxxxxxxx xxxxxx "která" x xxxxx "xxxxxxx" xx xxxxxxxxx slovem "xxxxxxx".

5. X §5 xxxx. 2 xxxx. a) xxxx 5 xx xxxxx "xxxxxxxxxxx" xxxxxxxxx xxxxxx "xxxxx", xxxxx "xxxxx" xx xxxxxxxxx xxxxxx "xxxxx" x xxxxx "xxxxx" se xxxxxxxxx xxxxxx "xxxxxx".

6. X §5 odstavec 3 zní:

"(3) Xxxxxx xxxxx xx xxxxxxxx xxx, xxx xxxxxxx xxxxx zůstal čitelný, x xxxxx xxxxxx xx xxxxxxxxx osobou xxxxxxx xxx xxxxxx xxxxxxxx, xxxxx x xxxxxxx xxxxxxx xxxxx xxxxxxxxx xxxxxx.".

7. X §7 odstavec 2 xxx:

"(2) Xxxxxxxxx xxxx Xxxxxxxx úřadu xxx xxxxxxxx xxxxxxxxxx xxxxxxxxx x elektronické xxxxx xxxxxxxxx xxxxxxxxx xxxxxxxxxxxxx xxxxxxxx, pokud xxxx xxxxxxxxx doručena xxxxxxxxxxxxxxx xxxxxx xxxxxxxx, nebo x xxxxxxxx xxxxx x xxxxxxxx xxxxxxxxxxxx xxxxxx x xxxxxxxx x elektronické xxxxx.".

8. Xxxxxxx č. 1 xxx:

"Xxxxxxx x. 1 x vyhlášce x. 474/2002 Sb.

Seznam xxxxxx xxxxxxxxxx xxxxxxxxxxxx agens x xxxxxx (§2 xxxx. d) zákona)

1. Xxxxxx xxxxxxxx x xxxxxxx zoonóz

1.1 Viry

1. xxxxx Xxxxx;

2. virus Xxxxxx;

3. xxxxx Xxxxx;

4. xxxxx Xxxxxxx;

5. xxxxx xxxxxxx údolí Xxxx (Xxxx Xxxxxx xxxxx xxxxx);

6. xxxxx Chikungunya;

7. xxxxx xxxxxxxx xxxxxxxxxxxx (Xxxxxxxx xxxxxxxxxxxx xxxxx);

8. xxxxx Junín;

9. xxxxx xxxxxxx-xxxxxxx xxxxxxxxxxx xxxxxxx (Xxxxxxx-Xxxxx xxxxxxxxxxxx fever xxxxx);

10. virus Lassa;

11. xxxxx Xxxx;

12. xxxxx xxxxxxxxxxxx choriomeningitidy;

13. virus Xxxxxxx;

14. xxxxx Xxxxxxx;

15. xxxxx opičích xxxxxxxx (Xxxxxxxxx virus);

16. xxxxx xxxxxxx xxxxxxxx (Variola xxxxx);

17. xxxxx Xxx Xxxxxx;

18. xxxxx xxxxxxxxxxx xxxxxx encefalomyelitidy (Venezuelan xxxxxx xxxxxxxxxxxx virus);

19. xxxxx xxxxxxxx xxxxxx xxxxxxxxxxxxxxxxx (Xxxxxxx xxxxxx xxxxxxxxxxxx virus);

20. xxxxx xxxxxxx xxxxxx xxxxxxxxxxxxxxxxx (Xxxxxxx equine xxxxxxxxxxxx xxxxx);

21. xxxxx žluté xxxxxxx (Xxxxxx fever xxxxx).

1.2 Xxxxxxxx

1. Xxxxxxxx xxxxxxxxx;

2. Xxxxxxxx xxxxxxx;

3. Xxxxxxxx melitensis;

4. Xxxxxxxx xxxx;

5. Burkholderia mallei (Xxxxxxxxxxx xxxxxx);

6. Xxxxxxxxxxxx xxxxxxxxxxxx (Xxxxxxxxxxx xxxxxxxxxxxx);

7. Xxxxxxxxxxx xxxxxxxxx;

8. Escherichia xxxx - shigatoxigenní xxxxx (XXXX) xxxxxxxxxxxx xxxxxx, xxxxxxxxxxx xxxxxx x hemolyticko-uremický syndrom x xxxx;

9. Xxxxxxxxxxx xxxxxxxxxx;

10. Xxxxxxxxxxxxx psittaci (Xxxxxxxxx psittaci);

11. Salmonella xxxxx (Xxxxxxxxxx enterica xxxxx. xxxxxxxx sérovar Xxxxx);

12. Xxxxxxxx xxxxxxxxxxx Xxx 1;

13. Xxxxxx xxxxxxxx;

14. Xxxxxxxx xxxxxx.

1.3 Xxxxxxxxxx

1. Xxxxxxxxxx quintana (Xxxxxxxxxx xxxxxxxx, Rickettsia xxxxxxxx);

2. Xxxxxxxx xxxxxxxx,

3. Xxxxxxxxxx prowazekii;

4. Rickettsia xxxxxxxxxx.

2. Patogeny xxxxxxxxx

2.1 Xxxx

1. xxxxx afrického xxxx koní (Xxxxxxx xxxxx xxxxxxxx virus);

2. xxxxx afrického xxxx xxxxxx (Xxxxxxx xxxxx xxxxx xxxxx);

3. xxxxx Xxxxxxxxxx xxxxxxx (Porcine xxxxxx virus (Xxxxxxxx'x xxxxxxx);

4. xxxxx influenzy xxxxxxx xxxxxxx (Xxxxx xxxxxxxxx xxxxx), x xx:

x. necharakterizovaný nebo

b. xxxxxxxxxx jako xxxxx x vysokou patogenitou, x xx:

1. xxxx xxxx A, xxxxx xxxx XXXX (index xxxxxxxxxx xxxxxxxxxx) x xxxxxxxxxxxxxx xxxxx xxxxx xxx 1,2 nebo

2. xxxx xxxx X xxxxxxx X5 xxxx X7, x nichž xxxxxxxxxxxx řetězce vykázaly xxxxxxx xxxxxxxx xxxxxxxxxxxxx xx štěpné xxxxxx xxxxxxxxxxxxx;

5. virus xxxxxxxxx xxxxxxx ovcí (Xxxxxxxxxx xxxxx);

6. virus xxxxxxxxxx xxxx prasat (Xxxxxxxxx xxxxx xxxxx xxxxx);

7. xxxxx xxxx xxxxxx xxxxxxxxxxx (Xxxxx xxx xxxxxx xxxxxxxxx xxxxx);

8. xxxxx xxxx skotu (Xxxxxxxxxx virus);

9. virus xxxxxxxx xxxx (Xxxxxxxx xxxxx);

10. virus xxxxxxxx xxx (Xxxxxxx xxxxx);

11. xxxxx xxxxxxxxxxxx xxxxxxx xxxxxxx (Xxxxxxxxx disease xxxxx);

12. xxxxx xxxxxxxxx xxxxxxxxxxx xxxxx (Xxxxx xxxx xxxxxxx virus);

13. xxxxx slintavky a xxxxxxxx (Xxxx-xxx-xxxxx disease xxxxx);

14. xxxxx Těšínské xxxxxxx, xxxxxxxxx obrny xxxxxx (Xxxxxxx disease xxxxx)

15. virus xxxxxxxxxxx xxxxxxx prasat (Xxxxx xxxxxxxxx xxxxxxx xxxxx);

16. xxxxx xxxxxxxxxxx xxxxxxxxxxx (Xxxxxxxxx xxxxxxxxxx virus);

17. xxxxx vztekliny (Lyssavirus).

2.2 Xxxxxxxxxx

1. Mycoplasma xxxxxxxx xxxxx. mycoides SC (xxxxx xxxxxx);

2. Xxxxxxxxxx xxxxxxxxxx xxxxx. xxxxxxxxxxxxxxx.

3. Xxxxxxxx xxxxxxx

3.1 Xxxx

1. xxxxxx xxxxxxxx tymovir xxxxxxxx (Andean potato xxxxxx virus);

2. xxxxxx xxxxxxxxxxxxxx xxxx xxxxxxxx (Xxxxxx spindle xxxxx xxxxxx).

3.2 Houby

1. Xxxxxxxxxxxx xxxxxxxxxx (Helminthosporium oryzae);

2. Xxxxxxxxxxx grisea (Xxxxxxxxxxx xxxxxx, xxx. Xxxxxxxxxxx xxxxxx);

3. Xxxxxxxxxxx xxxx (xxx. Xxxxxxxxxx xxxx).

4. Xxxxxx x xxxxxx xxxxxxxxxxx

1. abrin;

2. xxxxxxxxxx;

3. xxxxxxxx (xxxxxxxxxx cyanobakterií);

4. xxxxxxxxxx xxxxxx;

5. xxxxxxxxxxxx;

6. xxxxxxxxxx;

7. xxxxxxxxx;

8. xxxxxxxxxxxx;

9. xxxxxxxxxxx (xxxxxxxxxxx);

10. xxxxxxx;

11. xxxxx;

12. xxxxxxxxx;

13. xxxxx xxxxx, shiga xxxxxx 1 x 2 (xxxxxxxxxx) x proteiny xxxxxxx shiga xxxxxx, xxxxx inaktivují ribozomy;

14. xxxxxxxxxxxx;

15. xxxxxx Xxxxxxxxxxx xxxxxxxxxxx;

16. toxiny Xxxxxxxxxxxxxx xxxxxx;

17. xxxxxxxxxxxxxxx xxxxxx;

18. xxxxxxxx;

19. xxxxxxxxx.

5. Genetické xxxxxxxx x xxxxxxxxx xxxxxxxxxxxx xxxxxxxxx

5.1 Xxxxxxxxx xxxxxxxx, které xxxxxxxx xxxxxxxx xxxxxxxxxx kyselin xxxxxxxxxxx x patogenitou xxxxxxxxx uvedených x xxxxxx 1-3.

5.2 Genetické xxxxxxxx, které obsahují xxxxxxxx nukleových xxxxxxx xxxxxxxx xxxxxxx x xxxxxx xxxxxxxxx x xxxx 4 nebo xxxxxxxx podjednotky toxinů xxxxxxxxx x xxxx 4.

5.3 Xxxxxxxxx xxxxxxxxxxxx xxxxxxxxx, xxxxx xxxxxxxx xxxxxxxx nukleových kyselin xxxxxxxxxxx x patogenitou xxxxxxxxx uvedených x xxxxxx 1-3.

5.4 Geneticky xxxxxxxxxxxx xxxxxxxxx, xxxxx xxxxxxxx xxxxxxxx xxxxxxxxxx xxxxxxx xxxxxxxx xxxxxxx x xxxxxx xxxxxxxxx x xxxx 4 xxxx xxxxxxxx xxxxxxxxxxx xxxxxx xxxxxxxxx x xxxx 4.

5.5 De xxxx chemicky xxxxxxxxxxxxx xxxxxxxxx xxxxxxxx x xxxxx xxxxxxxxx xxxxxxxxx, xxxxx xxxxxxxx xxxxxxxx xxxxxxxxxx xxxxxxx xxxxxxxxxxx x patogenitou organismů xxxxxxxxx x xxxxxx 1-3.

5.6 Xx xxxx xxxxxxxx syntetizovaný xxxxxxxxx xxxxxxxx x xxxxx xxxxxxxxx xxxxxxxxx, xxxxx xxxxxxxx xxxxxxxx xxxxxxxxxx xxxxxxx xxxxxxxx některý x toxinů xxxxxxxxx x xxxx 4 xxxx kódující podjednotky xxxxxx xxxxxxxxx x xxxx 4.

Xxxxxxxx:

1) Mikroorganismy xxxxxxx x xxxx 1.2 9. xxxxxxxx xxxxxxx xxxxx xxxxxxxxxx X26, X45, O91, X103, O104, X111, X113, X121, X145, X157 x xxxxx, xxxxxxxxxxx shiga xxxxxx xx nesoucí xxxx xxxxxxxx jejich xxxxxxxx. Xxxxxxxx "xxxxxxxxxxxxxx xxxxx Xxxxxxxxxxx coli (XXXX)" xx ekvivalentní k xxxxxxxx "verotoxigenní kmeny Xxxxxxxxxxx xxxx (VTEC)".

2) Xxxxxxxx xxx xxxxxxxxx x toxiny xx xxxxxxxxxx xx xxxxxxxxxx xxxxxx (xxx 4.4.) xxxx xxxxxxxxxx (bod 4.7.) xxxxxxxx v xxxxxxxx přípravcích registrovaných xxxxx xxxxxx x xxxxxxxx.

3) Xxxxxxxxx xxxxxxxx xxxxxxxx xxxx jinými xxxxxxxxxx, genomy, xxxxxxxx, xxxxxxxxxxx x vektory, x to xxx xxxxxxxxx modifikované, xxx xxxxxxxxxxxxxx.

Xxxxxxxx nukleových xxxxxxx xxxxxxxxxxx x patogenitou xxxxxxxxx xxxxxxxxx x xxxxxx 1-3 představují xxxxxxxxx sekvenci xxxxxxxxxxx xxx xxxxxxx x xxxx xxxxxxxxx xxxxxxxxxxxxxx, xxxxx:

x) xxxx xxxxxx xxxx prostřednictvím svých xxxxxxxxxxxxxx xxxx xxxxxxxxxxxx xxxxxxxx představuje xxxxxxxx xxxxxxxxx xxx xxxxxx xxxx, xxxxxx xxxx xxxxxxx, nebo

b) xx xxxxx xxx, že x daného xxxxxxxxxxxxxx xxxx u jakéhokoli xxxxxx organismu, xx xxxxxxx může xxx xxxxxxx nebo xxxxx xxxxxxxxxxx, zvyšuje xxxx xxxxxxxxx xxxxxxxx xxxxx xxxxxxxxx zdraví xxxx, xxxxxx nebo xxxxxxx.

4) X xxxxxxxxxxxxxx xxxxxxxxx x xxxx 1.2 9 xx "xxxxxxxxx xxxxxxxx x geneticky xxxxxxxxxxxx xxxxxxxxx" podle xxxx 5 xxxxxxxx xxxxx xx xxxxxxxx xxxxxxxx kyseliny, které xxxxxx xxxxx toxiny (xxxxxxxxxx) x xxxxxxxx xxxxxxx xxxxx toxinu, xxxxx inaktivují xxxxxxxx, xxxx xxxxxx xxxxxxxxxxx.".

9. Xxxxxxx x. 2 xxx:

"Xxxxxxx x. 2 x xxxxxxxx č. 474/2002 Sb.

Seznam xxxxxxxxxx xxxxxxxxxxxx agens a xxxxxx (§2 xxxx. x) xxxxxx)

X. Xxxx

1. xxxxx australské xxxxxxxxxxxx (Xxxxxx Xxxxxx encephalitis xxxxx);

2. xxxxx Xxxxxxx-Xxxxxxxx;

3. xxxxx xxxxxxxxxxxx St. Xxxxx (St. Louis xxxxxxxxxxxx xxxxx);

4. xxxxx Xxxxxx;

5. xxxxx Guanarito;

6. xxxxx Hendra (Xxxxxx xxxxxxxx xxxxx);

7. virus xxxxxxx Xxxxxxxxxxxxx lesa (Xxxxxxxx forest disease xxxxx);

8. xxxxx Xxxxxxx;

9. xxxxx Choclo;

10. xxxxx xxxxxxxx xxxxxxxxxxxx, xxxxx xxxxx jaro-letní xxxxxxxxxxxx (Xxxx-xxxxx encephalitis virus, Xxxxxxx Xxxxxx-Xxxxxx xxxxxxxxxxxx xxxxx);

11. xxxxx Xxxxxx Xxxxx;

12. virus Xxxxx;

13. xxxxx Xxxxxxxxx;

14. xxxxx Xxxxx xxxxxxxxxxx xxxxxxx (Xxxx hemorrhagic fever xxxxx);

15. xxxxx Xxxxxxxx;

16. xxxxx Xxxxxxx,

17. virus Xxxxx;

18. xxxxx Xxxxx,

19. xxxxx Xxxxx;

20. xxxxx xxxxxxx (Xxxxxxx ill xxxxx);

21. xxxxx západonilské xxxxxxx (Xxxx Nile xxxxx).

XX. Xxxxxxxx

1. Xxxxxxxxxxx xxxxxxxxxxx - xxxxx xxxxxxxxxxx xxxxxxx xxxxx;

2. Xxxxxxxxxxx xxxxxx;

3. Legionella xxxxxxxxxxx;

4. Mycobacterium bovis (x xxxxxxxx xxxxx XXX);

5. Mycobacterium tuberculosis (xxxxxxxxxxxxxxxx kmeny);

6. Xxxxxxxxxxx xxxxxxxxxxx;

7. Xxxxxxxxxxx xxxxxxxxxx xx. xxxxx včetně xxxxx xxxxxxxxxxxx xxxx Xxxxxxxxxxx xxxxxxxxxx pv. xxxxx xxxx X, X, C, D, X xxxx xxxxx xxxxxxxxxxxxx xxxx Xxxxxxxxxxx xxxxx, Xxxxxxxxxxx campestris xx. xxxxxxxxxxxx xxxx Xxxxxxxxxxx xxxxxxxxxx pv. Xxxxxxxxx;

8. Xxxxxxxx xxxxxxxxxxxxxxxxxx.

XXX. Xxxxx

1. Xxxxxxxxxxxx immitis;

2. Xxxxxxxxxxxx xxxxxxxxx;

3. Xxxxxxxxxxxxxx xxxxxxxxx xxx. Xxxxxxxx (Xxxxxxxxxxxxxx xxxxxxx);

4. Xxxxxxxx xxxxxxxx (syn. Xxxxxxxx xxxxxxxx x. sp. xxxxxxx);

5. Puccinia striiformis (xxx. Xxxxxxxx xxxxxxxx).

XX. Xxxxxx a xxxxxx xxxxxxxxxxx

1. Xxxxxxxxxxx.

X. Xxxxxxxxx xxxxxxxx a xxxxxxxxx xxxxxxxxxxxx xxxxxxxxx

1. Xxxxxxxxx xxxxxxxx, xxxxx xxxxxxxx xxxxxxxx xxxxxxxxxx xxxxxxx xxxxxxxxxxx x xxxxxxxxxxx xxxxxxxxx uvedených x xxxxxx X-XXX.

2. Xxxxxxxxx elementy, xxxxx xxxxxxxx xxxxxxxx xxxxxxxxxx xxxxxxx xxxxxxxx xxxxxxx x xxxxxx uvedených x xxxx XX xxxx kódující xxxxxxxxxxx xxxxxx xxxxxxxxx x xxxx XX.

3. Geneticky xxxxxxxxxxxx organismy, které xxxxxxxx sekvence xxxxxxxxxx xxxxxxx xxxxxxxxxxx s xxxxxxxxxxx xxxxxxxxx uvedených x bodech I-III..

4. Xxxxxxxxx xxxxxxxxxxxx xxxxxxxxx, xxxxx xxxxxxxx sekvence xxxxxxxxxx xxxxxxx kódující xxxxxxx x xxxxxx xxxxxxxxx x bodě XX xxxx xxxxxxxx xxxxxxxxxxx xxxxxx xxxxxxxxx x xxxx IV.

5. Xx xxxx xxxxxxxx xxxxxxxxxxxxx xxxxxxxxx materiál x xxxxx xxxxxxxxx xxxxxxxxx, které xxxxxxxx xxxxxxxx xxxxxxxxxx kyselin xxxxxxxxxxx x xxxxxxxxxxx xxxxxxxxx xxxxxxxxx x xxxxxx X-XXX.

6. Xx xxxx chemicky xxxxxxxxxxxxx xxxxxxxxx xxxxxxxx x xxxxx vytvořené organismy, xxxxx xxxxxxxx sekvence xxxxxxxxxx xxxxxxx xxxxxxxx xxxxxxx x xxxxxx xxxxxxxxx x bodě XX xxxx xxxxxxxx xxxxxxxxxxx toxinů uvedených x bodě IV.

Poznámky:

Genetické xxxxxxxx xxxxxxxx xxxx xxxxxx xxxxxxxxxx, genomy, xxxxxxxx, xxxxxxxxxxx a xxxxxxx, x to xxx geneticky xxxxxxxxxxxx, xxx xxxxxxxxxxxxxx.

Xxxxxxxx xxxxxxxxxx xxxxxxx související x xxxxxxxxxxx xxxxxxxxx uvedených x xxxxxx X-xxX xxxxxxxxxxx jakoukoli xxxxxxxx xxxxxxxxxxx pro xxxxxxx x xxxx uvedených xxxxxxxxxxxxxx, xxxxx:

x) xxxx xxxxxx xxxx xxxxxxxxxxxxxxx xxxxx xxxxxxxxxxxxxx xxxx xxxxxxxxxxxx xxxxxxxx xxxxxxxxxxx xxxxxxxx nebezpečí xxx xxxxxx osob, xxxxxx xxxx xxxxxxx, nebo

b) xx xxxxx xxx, xx x xxxxxx xxxxxxxxxxxxxx nebo u xxxxxxxxxx xxxxxx xxxxxxxxx, xx xxxxxxx xxxx xxx xxxxxxx nebo xxxxx xxxxxxxxxxx, xxxxxxx xxxx xxxxxxxxx způsobit xxxxx poškození xxxxxx xxxx, xxxxxx nebo xxxxxxx.".