Právní předpis byl sestaven k datu 09.02.2026.
Zobrazené znění právního předpisu je účinné od 10.12.2024.
Sdělení Ministerstva zdravotnictví o antigenním složení očkovacích látek pro pravidelná, zvláštní a mimořádná očkování pro rok 2025
375/2024 Sb.
375
SDĚLENÍ
Ministerstva xxxxxxxxxxxxx
xx dne 5. prosince 2024
x xxxxxxxxxx složení xxxxxxxxxx xxxxx xxx xxxxxxxxxx, xxxxxxxx a mimořádná xxxxxxxx pro xxx 2025
&xxxx;
Xxxxxxxxxxxx xxxxxxxxxxxxx podle §80 xxxx. 1 xxxx. x) zákona x. 258/2000 Sb., x xxxxxxx xxxxxxxxx xxxxxx x o xxxxx xxxxxxxxx xxxxxxxxxxxxx xxxxxx, ve xxxxx xxxxxxxxxx xxxxxxxx, stanoví xx xxxxxxx doporučení Xxxxxxx xxxxxxxxxx komise xxxxxxxxx xxxxxxx xxxxxxxxxx xxxxx xxx pravidelná, xxxxxxxx a xxxxxxxxx xxxxxxxx xxx rok 2025:
1. Xxxxxxxxx xxxxxxx xxxxxxxxxx látek xxx xxxxxxxxxx xxxxxxxx
1x) kombinovaná xxxxxxxx látka xxxxx xxxxxxx, xxxxxxxx kašli (xxxxxxxxxx xxxxx), xxxxxx, xxxxxx xxxxxxxx xxxxx (xxxxxxxxxxxx forma), virové xxxxxxxxxx X, xxxxxxx xxxxxxxxx Haemophilus xxxxxxxxxx xxx x (XXxXXxxXXXXXX)
Xx xxxxxxxxxxxx 1 xxxxx (0,5 ml) obsahuje:
Diphtheriae xxxxxxxxxx1 ne xxxx xxx 30 mezinárodních xxxxxxxx (XX)
Xxxxxx xxxxxxxxxx1 xx xxxx xxx 40 xxxxxxxxxxxxx jednotek (XX)
Xxxxxxxx Xxxxxxxxxx xxxxxxxxx:
Xxxxxxxxx xxxxxxxxxx (XX)1 25 xxxxxxxxxx
Xxxxxxxxx xxxxxxxxxxxxxxxx xxxxxxxxxxxx (XXX)1 25 xxxxxxxxxx
Xxxxxxxxxxx (XXX)1 8 xxxxxxxxxx
Xxxxxxxxx xxxxxxxxx xxxxxxxxxxx B (XXx)2,3 10 xxxxxxxxxx
Xxxxx xxxxxxxxxxxxxxx inactivatum (XXX)
xx xxx 1 (xxxx Xxxxxxx)4 40 X xxxxxxxx xxxxxxxx
xxxxx 2 (xxxx MEF-1)4 8 X xxxxxxxx xxxxxxxx
xxxxx 3 (xxxx Xxxxxxx)4 32 X jednotek xxxxxxxx
Xxxxxxxxxxx xxxxxxxxxx xxxxx x xxxxxxxxxxxxxxx
(Xxxxxxxxxxxxxxxxxxx phosphas) 10 xxxxxxxxxx
xxxx. cum xxxxxx. tetanico xxxx xxxxx protein přibližně 25 xxxxxxxxxx
1 adsorbováno xx hydroxid hlinitý, xxxxxxxxxxx (Xx(XX)3) 0,5 xxxxxxxxx Al3+
2 xxxxxxxx xxxxxxxxxxxxx XXX technologií xx xxxxxxx xxxxxxxxxxxx xxxxx (Xxxxxxxxxxxxx cerevisiae)
3 xxxxxxxxxxx xx fosforečnan xxxxxxx (XxXX4) 0,32 xxxxxxxxx Al3+
4 xxxxxxxxx xx XXXX buňkách
NEBO
1aa) xxxxxxxxxxx očkovací xxxxx xxxxx xxxxxxx, xxxxxxxx xxxxx (acelulární xxxxx), xxxxxx, xxxxxx xxxxxxxx xxxxx (inaktivovaná xxxxx), xxxxxx hepatitidě X, xxxxxxx vyvolaným Xxxxxxxxxxx xxxxxxxxxx typ b (XXxXXxxXXXXXX)
Xxxxx dávka1 (0,5 xx) xxxxxxxx:
Xxxxxxxxxxx xxxxxxxxxx xx xxxx než 20 xxxxxxxxxxxxx jednotek (XX)2,4 (30 Lf)
Tetani xxxxxxxxxx xx méně xxx 40 mezinárodních xxxxxxxx (XX)3,4 (10 Xx)
Xxxxxxxx Xxxxxxxxxx xxxxxxxxx
Xxxxxxxxx xxxxxxxxxx 25 xxxxxxxxxx
Xxxxxxxxx xxxxxxxxxxxxxxxx filamentosum 25 xxxxxxxxxx
Xxxxx Xxxxxxxxxxxxxxx (xxxxxxxxxxxx)5
xxxxx 1 (Xxxxxxx) 29 X jednotek xxxxxxxx6
xxxxx 2 (MEF-1) 7 X xxxxxxxx xxxxxxxx6
xxxxx 3 (Saukett) 26 X xxxxxxxx antigenu6
Tegiminis xxxxxxxxxxx B xxxxxxxxx7 10 xxxxxxxxxx
Xxxxxxxxxx xxxxxxxxxx xxxx X xxxxxxxxxxxxxxx (Xxxxxxxxxxxxxxxxxxx xxxxxxxx) 12 xxxxxxxxxx xxxxxxxxxx cum xxxxxx xxxxxxxx 22-36 xxxxxxxxxx
1 Xxxxxxxxxxx xx xxxxxxxxxxx xxxxxxxx hlinitý (0,6 xx Xx3+)
2 Xxxx spodní mez xxxxxxxxxxxxx (x = 0,95) a ne xxxx xxx 30 XX xxxx xxxxxxx xxxxxxx
3 Xxxx spodní xxx xxxxxxxxxxxxx (x = 0,95)
4 Nebo xxxxxxxxxxxx xxxxxxxx stanovená xxxxxxxxxx imunogenity
5 Xxxxxxxxxxx xx Vero xxxxxxx
6 Xxxx xxxxxxxx antigenu xxxx xxxxx stejná xxxx xx, xxxxx xxxx dříve xxxxxxxxx xxxx 40-8-32 X xxxxxxxx xxxxxxxx xxx xxxxx xxxx 1, 2 x 3, xxx xxxxxx xxxxx xxxxxxx xxxxxxxxxxxxxx xxxxxxx
7 xxxxxxxx xxxxxxxxxxxxx XXX xxxxxxxxxxx v kvasinkových xxxxxxx Xxxxxxxxx xxxxxxxxxx
XXXX
1xx) Xxxxxxx xxxxx xxxxxxx, xxxxxx, dávivému kašli (xxxxxxxxxx xxxxxxxxxx), xxxxxxxxxx X (xXXX), dětské xxxxxxxx obrně (xxxxxxxxxxxx) x konjugovaná xxxxxxx xxxxx Xxxxxxxxxxx typu x (xxxxxxxxxxx)
Xxxxx xxxxx (0,5 ml) obsahuje:
Diphtheriae xxxxxxxxxx1 ne xxxx xxx 20 XX6
Xxxxxx xxxxxxxxxx1 xx xxxx xxx 40 XX6
Xxxxxxxx Xxxxxxxxxxx pertusis1
Pertussis anatoxinum (XX) 20 xxxxxxxxxx
Xxxxxxxxxxxxxxx xxxxxxxxxxxx (XXX) 20 xxxxxxxxxx
Xxxxxxxxxxx (XXX) 3 xxxxxxxxxx
Xxxxxxxx typi 2 xx 3 (XXX) 5 mikrogramů
Antigenum xxxxxxxxx xxxxxxxxxxx B 2,3 10 xxxxxxxxxx
Xxxxx xxxxxxxxxxxxxxx (xxxxxxxxxxx)4
Xxxxx 1 (Mahoney) 40 X xxxxxxxx xxxxxxxx5
Xxxxx 2 (MEF-1) 8 D xxxxxxxx xxxxxxxx5
Xxxxx 3 (Xxxxxxx) 32 X xxxxxxxx xxxxxxxx5
Xxxxxxxxxxxxxx Xxxxxxxxxx xxxxxxxxxx xxxxx b
(Polyribosylribitoli xxxxxxxx) 3 xxxxxxxxxx conjunctum xxx xxxxxxxxx xxxxxxxxxxxx xxxxx x2 50 xxxxxxxxxx
1 xxxxxxxxxxx xx xxxxxxxxxxx hlinitý (0,17 xx Xx3+)
2 adsorbováno xx xxxxxxxxxxx hydroxid xxxxxxx sulfát (0,15 xx Al3+)
3 xxxxxxxx xxxxxxxxxxxxx XXX xxxxxxxxxxx x xxxxxxxxxxxx buňkách Xxxxxxxxxxxxx xxxxxxxxxx
4 xxxxxxxxx xx Xxxx xxxxxxx
5 xxxx xxxxxxxxxxxx xxxxxxxx xxxxxxxx xxxxxxxxx xxxxxxx xxxxxxxxxxxxxx xxxxxxx
6 xxxx xxxxxxxxxxxx xxxxxxxx xxxxxxxxx xxxxxxxxxxxx imunogenity
1b) očkovací xxxxx proti xxxxxxx, xxxxxxxx xxxxx (acelulární xxxxx), xxxxxx (XXxX)
Xxxxx xxxxx (0,5 ml) xxxxxxxx tyto xxxxxx xxxxx:
Xxxxxxxxxxx xxxxxxxxxx* ≥ 30 XX
Xxxxxx anatoxinum* ≥ 40 IU
Pertussis xxxxxxxxxx* (XX) 25 xxxxxxxxxx
Xxxxxxxxx xxxxxxxxxxxxxxx xxxxxxxxxxxx* (XXX) 25 xxxxxxxxxx
Xxxxxxxxxxx* (69xX) 8 xxxxxxxxxx
* xxxxxxxxxxx na hydroxid xxxxxxx xxxxxx: 0,5 xxxxxxxxx
XXXX
1xx) Xxxxxxxx xxxxx xxxxx záškrtu, tetanu x dávivému kašli (xxxxxxxxxx) xx sníženým xxxxxxx antigenů (Tdap)
Jedna xxxxx (0,5 xx) xxxxxxxx:
Xxxxxxxxxxx xxxxxxxxxx - Xxxxxxxxx 2 XX* (2 Xx)
Xxxxxx xxxxxxxxxx - Minimálně 20 XX* (5 Lf)
Pertusové xxxxxxxx
Xxxxxxxxx xxxxxxxxxx - 2,5 xxxxxxxxxx
Xxxxxxxxxxxxxx xxxxxxxxxxxx - 5 xxxxxxxxxx
Xxxxxxxxxxx - 3 xxxxxxxxxx
Xxxxxxxx, xxxx 2 et 3 - 5 xxxxxxxxxx
Xxxxxxxxxxx xx xxxxxxxxxxx xxxxxxx - 1,5 xx (0,33 xx xxxxxxx)
* Xxxx xxxxxx xxxxxxx xxxxxxxxx xxxxxxxxxxxxx (x = 0,95) xxxxxxxx měřené xxxxx xxxxx popsaného x Xxxxxxxxx xxxxxxxx
XXXX
1xx) Xxxxxxxx xxxxx xxxxx xxxxxxx, xxxxxx a xxxxxxxx xxxxx (xxxxxxxxxx komponenta) xx xxxxxxxx xxxxxxx xxxxxxxx (Tdap)
Jedna dávka (0,5 xx) obsahuje:
Diphtheriae xxxxxxxxxx1 xx xxxx xxx 2 xxxxxxxxxxx xxxxxxxx (XX) (2,5 Xx)
Xxxxxx anatoxinum1 xx xxxx xxx 20 xxxxxxxxxxxxx xxxxxxxx (IU) (5 Xx)
Xxxxxxxxxxx xxxxxxxxx xxxxxxxx:
Xxxxxxxxx anatoxinum1 8 xxxxxxxxxx
Xxxxxxxxx xxxxxxxxxxxxxx xxxxxxxxxxxx1 8 xxxxxxxxxx
Xxxxxxxxxxx1 2,5 xxxxxxxxxx
1 xxxxxxxxxxx xx xxxxxxxxxxx hydroxid hlinitý (X1(XX)3) 0,3 xxxxxxxxx Xx3+ x fosforečnan xxxxxxx (AlPO4) 0,2 xxxxxxxxx Al3+
1c) xxxxxxxx xxxxx proti nákazám xxxxxxxxx Haemophilus influenzae xxx b:
Po rekonstituci 1 xxxxx (0,5 xx) xxxxxxxx:
Xxxxxxxxxxx xxxxxxxxxx xxxxx b xxxx xxxxxxxxxxx 10 mikrogramů
konjugovaný x tetanickým xxxxxxxx xxxx xxxxxxxxxxx xxxxxxx xxxxxxxxx 25 xxxxxxxxxx
1x) xxxxxxxx xxxxx xxxxx xxxxxx:
Xxxxx xxxxx xxxxxxxx:
Xxxxxx xxxxxxxxxx - min. 40 mezinárodních xxxxxxxx
1x) xxxxxxxx xxxxx proti xxxxxx xxxxxxxxxx B x dětské xxxxxxx:
Xxxxx xxxxx xxxxxxxx:
Xxxxxxxxx xxxxxxxxx xxxxxxxxxxx B - 10 mikrogramů
1f) xxxxxxxx xxxxx xxxxx xxxxxx xxxxxxxxxx X x xxxxxxx formuli
Jedna dávka xxxxxxxx:
Xxxxxxxxx tegiminis xxxxxxxxxxx X - 20 xxxxxxxxxx
1x) xxxxxxxx xxxxx xxxxx spalničkám, xxxxxxxxxx x xxxxxxxxx:
xxxxx rekonstituované xxxxxxx (0,5 ml) xxxxxxxx:
Xxxxxxxxxxx xxxxx xxxxxxxxxx1 (Xxxxxxx) xxx. 103,0 xxxxxxxx xxxxx xxx xxxxxxxx xxxxxxx503
Xxxxxxxxxxx virus xxxxxxxxxx1 (XXX 4385) xxx. 103,7 xxxxxxxx xxxxx pro xxxxxxxx xxxxxxx503
Xxxxxxxx xxxxx attenuatum2 (Xxxxxx XX 27/3) xxx. 103,0 xxxxxxxx xxxxx xxx buněčnou xxxxxxx503
1 xxxxxxxxx xx xxxxxxx xxxxxxxx xxxxxx
2 xxxxxxxxx xx xxxxxxxx xxxxxxxxxxx buňkách (XXX-5)
3 50% infekční dávka xxxxxxx xxxxxxx
XXXX
1xx) xxxxxxxx xxxxx xxxxx xxxxxxxxxx, xxxxxxxxxx a zarděnkám
Po xxxxxxxxxx obsahuje jedna xxxxx (0,5 xx):
Xxxxx xxxxxxxxxxx1 xxxxx attenuatum (xxxx Xxxxxx’ Xxxxxxxxx) xx méně xxx 1x103 XXXX50*
Xxxxx xxxxxxxxxxx1 xxxxx xxxxxxxxxx (xxxx Xxxxx Xxxx™, xxxxxxx X) ne méně xxx 12,5x103 XXXX50*
Xxxxx xxxxxxxx2 xxxxx xxxxxxxxxx (xxxx Wistar XX 27/3) xx xxxx xxx 1x103 XXXX50*
* 50% infekční xxxxx xxxxxxx xxxxxxx
1 xxxxxxxx xx buňkách xxxxxxxx xxxxxx.
2 xxxxxxxx xx xxxxxxxx diploidních xxxxxxxx XX-38 xxxxxxxxxxxxx
1x) xxxxxxxx xxxxx xxxxx xxxxxx xxxxxxxx obrně x xxxxxxxxxxxx xxxxx:
Xxxxx xxxxx (0,5 xx) obsahuje:
Virus xxxxxxxxxxxxx inactivatum typus 1 (Xxxxxxx) ... 29 xxxxxxxxxxx D xxxxxxxx**
Xxxxx poliomyelitis xxxxxxxxxxx xxxxx 2 (XXX-1) ... 7 xxxxxxxxxxx X xxxxxxxx**
Xxxxx poliomyelitis xxxxxxxxxxx xxxxx 3 (Xxxxxxx) ) ... 26 xxxxxxxxxxx X xxxxxxxx**
* Kultivováno na XXXX xxxxxxx
** Xxxx xxxxxxxx xxxxxxxx xxxx xxxxx xxxxxx xxxx xx, xxxxx xxxx xxxxx vyjádřená xxxx 40-8-32 X xxxxxxxx xxxxxxxx pro virus xxxx 1, 2 x 3, xxx xxxxxx jinou vhodnou xxxxxxxxxxxxxx xxxxxxx
1xx) xxxxxxxxxxx xxxxxxxx xxxxx proti xxxxxxxxxxxxx xxxxxxxx
Xxxxx dávka (0,5 ml) obsahuje:
Polysacharid xxxxxxxx (xxxxxxxxxx) Streptococcus xxxxxxxxxx sérotypu 1 1,2 2,2 µx
xxxxxxxxxxxx xxxxxxxx (xxxxxxxxxx) Xxxxxxxxxxxxx xxxxxxxxxx xxxxxxxx 3 1,2 2,2 µg
polysacharid xxxxxxxx (xxxxxxxxxx) Xxxxxxxxxxxxx xxxxxxxxxx xxxxxxxx 4 1,2 2,2 µg
polysacharid xxxxxxxx (pneumokoka) Xxxxxxxxxxxxx xxxxxxxxxx xxxxxxxx 5 1,2 2,2 µg
polysacharid xxxxxxxx (xxxxxxxxxx) Xxxxxxxxxxxxx xxxxxxxxxx xxxxxxxx 6A 1,2 2,2 µx
xxxxxxxxxxxx xxxxxxxx (pneumokoka) Xxxxxxxxxxxxx xxxxxxxxxx xxxxxxxx 6X 1,2 4,4 µx
xxxxxxxxxxxx xxxxxxxx (xxxxxxxxxx) Xxxxxxxxxxxxx xxxxxxxxxx xxxxxxxx 7F 1,2 2,2 µx
xxxxxxxxxxxx xxxxxxxx (pneumokoka) Xxxxxxxxxxxxx xxxxxxxxxx xxxxxxxx 8 1,2 2,2 µx
xxxxxxxxxxxx xxxxxxxx (xxxxxxxxxx) Xxxxxxxxxxxxx xxxxxxxxxx xxxxxxxx 9 X 1,2 2,2 µx
xxxxxxxxxxxx xxxxxxxx (xxxxxxxxxx) Xxxxxxxxxxxxx xxxxxxxxxx sérotypu 10X 1,2 2,2 µx
xxxxxxxxxxxx xxxxxxxx (pneumokoka) Xxxxxxxxxxxxx pneumoniae sérotypu 11X 1,2 2,2 µx
xxxxxxxxxxxx xxxxxxxx (pneumokoka) Xxxxxxxxxxxxx xxxxxxxxxx xxxxxxxx 12X 1,2 2,2 µx
xxxxxxxxxxxx xxxxxxxx (xxxxxxxxxx) Xxxxxxxxxxxxx xxxxxxxxxx xxxxxxxx 14 1,2 2,2 µx
xxxxxxxxxxxx bakterie (xxxxxxxxxx) Xxxxxxxxxxxxx xxxxxxxxxx xxxxxxxx 15X 1,2 2,2 µx
xxxxxxxxxxxx bakterie (xxxxxxxxxx) Xxxxxxxxxxxxx pneumoniae sérotypu 18X 1,2 2,2 µx
xxxxxxxxxxxx xxxxxxxx (xxxxxxxxxx) Xxxxxxxxxxxxx xxxxxxxxxx xxxxxxxx 19X 1,2 2,2 µx
xxxxxxxxxxxx xxxxxxxx (xxxxxxxxxx) Xxxxxxxxxxxxx pneumoniae sérotypu 19X 1,2 2,2 µx
xxxxxxxxxxxx xxxxxxxx (xxxxxxxxxx) Xxxxxxxxxxxxx xxxxxxxxxx sérotypu 22X 1,2 2,2 µx
xxxxxxxxxxxx bakterie (pneumokoka) Xxxxxxxxxxxxx xxxxxxxxxx sérotypu 23X 1,2 2,2 µx
xxxxxxxxxxxx xxxxxxxx (pneumokoka) Xxxxxxxxxxxxx xxxxxxxxxx xxxxxxxx 33X 1,2 2,2 µx
1 Xxxxxxxxxx s xxxxxx xxxxxxxxx CRM197 (xxxxxxxxx 51 µx xx xxxxx)
2 Adsorbován xx xxxxxxxxxxx xxxxxxx (0,125 mg hliníku xx xxxxx)
XXXX
1xxx) xxxxxxxx xxxxx proti xxxxxxxxxxxxx xxxxxxxx xxxxxxxxx x xxxxxxxxxx xxxxxxxx:
1xxxx) xxxxxxxxxxx xxxxxxxx látka xxxxxxxx:
Xxxxxxxxxxxx xxxxxxxxxx serotypi 11,2 xxxxxxxxxxxxxxx 2,0 mikrogramů
Streptococci xxxxxxxxxx serotypi 31,2 xxxxxxxxxxxxxxx 2,0 mikrogramů
Streptococci xxxxxxxxxx xxxxxxxx 41,2 xxxxxxxxxxxxxxx 2,0 mikrogramů
Streptococci xxxxxxxxxx serotypi 51,2 xxxxxxxxxxxxxxx 2,0 xxxxxxxxxx
Xxxxxxxxxxxx xxxxxxxxxx xxxxxxxx 6X1,2 xxxxxxxxxxxxxxx 2,0 xxxxxxxxxx
Xxxxxxxxxxxx xxxxxxxxxx serotypi 6B1,2 xxxxxxxxxxxxxxx 4,0 mikrogramů
Streptococci xxxxxxxxxx xxxxxxxx 7X1,2 xxxxxxxxxxxxxxx 2,0 xxxxxxxxxx
Xxxxxxxxxxxx xxxxxxxxxx serotypi 9X1,2 xxxxxxxxxxxxxxx 2,0 xxxxxxxxxx
Xxxxxxxxxxxx xxxxxxxxxx xxxxxxxx 141,2 xxxxxxxxxxxxxxx 2,0 xxxxxxxxxx
Xxxxxxxxxxxx xxxxxxxxxx xxxxxxxx 18C1,2 xxxxxxxxxxxxxxx 2,0 xxxxxxxxxx
Xxxxxxxxxxxx xxxxxxxxxx serotypi 19X1,2 xxxxxxxxxxxxxxx 2,0 xxxxxxxxxx
Xxxxxxxxxxxx xxxxxxxxxx sérotypu 19X1,2 xxxxxxxxxxxxxxx 2,0 mikrogramů
Streptococci xxxxxxxxxx xxxxxxxx 22F1,2 xxxxxxxxxxxxxxx 2,0 xxxxxxxxxx
Xxxxxxxxxxxx xxxxxxxxxx serotypi 23X1,2 xxxxxxxxxxxxxxx 2,0 xxxxxxxxxx
Xxxxxxxxxxxx xxxxxxxxxx xxxxxxxx 33X1,2 xxxxxxxxxxxxxxx 2,0 mikrogramů
1 Xxxxxxxxxx x xxxxxxxxxxx xxxxxxx XXX197, XXX197 xx xxxxxxxxx xxxxxx xxxxxxxxxxxx xxxxxx (xxxxxxxxxxxxx x Corynebacterium diphtheriae X7) xxxxxxxxxxxxx xxxxxxxxxxxxx x Xxxxxxxxxxx xxxxxxxxxxx
2 Xxxxxxxxxx xx xxxxxxxx xxxxxxxxxxx xxxxxxx
X
1xxxx) póly xxxxxxxxxxx očkovací xxxxx xxxxxxxx:
xx 25 mikrogramech xxxxxxxxxxxxx 23 pneumokokových xxxxxxxxxxxxxxxxx sérotypů: 1, 2, 3, 4, 5, 6B, 7X, 8, 9X, 9V, 10X, 11X, 12X, 14, 15B, 17X, 18X, 19F, 19X, 20, 22X, 23X, 33X
XXXX
1xxx) očkovací xxxxx xxxxx xxxxxxxxxxxxx infekcím xxxxxxxxx x xxxxxxxxxx xxxxxxxx:
1xxxx) xxxxxxxxxxx očkovací xxxxx xxxxxxxx:
Xxxxxxxxxxxx pneumoniae xxxxxxxxxxxxxxx sérotypus 11 2,2µx
Xxxxxxxxxxxx pneumoniae xxxxxxxxxxxxxxx xxxxxxxxx 31 2,2 µx
Xxxxxxxxxxxx xxxxxxxxxx xxxxxxxxxxxxxxx xxxxxxxxx 41 2,2 µx
Xxxxxxxxxxxx pneumoniae polysaccharidum xxxxxxxxx 51 2,2 µx
Xxxxxxxxxxxx pneumoniae xxxxxxxxxxxxxxx xxxxxxxxx 6X1 2,2 µx
Xxxxxxxxxxxx pneumoniae xxxxxxxxxxxxxxx xxxxxxxxx 6B1 4,4 µx
Xxxxxxxxxxxx xxxxxxxxxx xxxxxxxxxxxxxxx xxxxxxxxx 7X1 2,2 µx
Xxxxxxxxxxxx pneumoniae polysaccharidum xxxxxxxxx 9X1 2,2 µx
Xxxxxxxxxxxx pneumoniae polysaccharidum xxxxxxxxx 141 2,2 µx
Xxxxxxxxxxxx xxxxxxxxxx polysaccharidum xxxxxxxxx 18X1 2,2 µx
Xxxxxxxxxxxx xxxxxxxxxx xxxxxxxxxxxxxxx xxxxxxxxx 19A1 2,2 µx
Xxxxxxxxxxxx xxxxxxxxxx xxxxxxxxxxxxxxx xxxxxxxxx 19F1 2,2 µx
Xxxxxxxxxxxx xxxxxxxxxx xxxxxxxxxxxxxxx xxxxxxxxx 23X1 2,2 µx
1 Xxxxxxxxxx x xxxxxx xxxxxxxxx CRM197 x xxxxxxxxxx xx xxxxxxxxxxx hlinitý (0,125 xx xxxxxxx)
X
1xxxx) xxxx xxxxxxxxxxx xxxxxxxx xxxxx xxxxxxxx:
xx 25 xxxxxxxxxxxx xxxxxxxxxxxxx 23 pneumokokových xxxxxxxxxxxxxxxxx sérotypů: 1, 2, 3, 4, 5, 6X, 7X, 8, 9X, 9V, 10X, 11X, 12X, 14, 15X, 17X, 18X, 19F, 19X, 20, 22F, 23F, 33X
1x) očkovací látka xxxxx xxxxxxx, xxxxxxxx xxxxx (acelulární xxxxx), xxxxxx, xxxxxx xxxxxxxx xxxxx (xxxxxxxxxxxx forma):
Jedna xxxxx (0,5 xx) xxxxxxxx:
Xxxxxxxxxxx xxxxxxxxxx1 - xx xxxx xxx 2 xxxxxxxxxxx xxxxxxxx (XX) (2,5 Xx)
Xxxxxx xxxxxxxxxx1-&xxxx; ne xxxx xxx 20 xxxxxxxxxxxxx xxxxxxxx (XX) (5 Xx)
Xxxxxxxxxxx pertussis xxxxxxxx:
Xxxxxxxxx xxxxxxxxxx1 - 8 xxxxxxxxxx
Xxxxxxxxx haemagglutinum xxxxxxxxxxxx1 - 8 mikrogramů
Pertaktin1 2,5 mikrogramů
Virus poliomyelitidis xxxxxxxxxxx:
xxxxx 1 (kmen Xxxxxxx)2 40 X xxxxxxxx xxxxxxxx
xxxxx 2 (xxxx XXX-1)2 8 X jednotek xxxxxxxx
xxxxx 3 (xxxx Saukett)2 32 X xxxxxxxx xxxxxxxx
1 adsorbováno xx xxxxxxxxxxx xxxxxxxx xxxxxxx (Xx(XX)3) 0,3 xxxxxxxxx Xx3+ x fosforečnan xxxxxxx (XxXX4) 0,2 xxxxxxxxx Xx3+
2 xxxxxxxxx xx VERO xxxxxxx
XXXX
1xx) xxxxxxxx xxxxx xxxxx xxxxxxx, xxxxxxxx xxxxx (xxxxxxxxxx forma), xxxxxx, xxxxxx přenosné xxxxx (xxxxxxxxxxxx forma):
Jedna dávka (0,5 xx) xxxxxxxx:
Xxxxxxxxxxx xxxxxxxxxx xxxxxxxxx 2 XX1 (2 Xx)
Xxxxxx xxxxxxxxxx xxxxxxxxx 20 XX1 (5 Xx)
Xxxxxxxxx xxxxxxxx:
Xxxxxxxxx xxxxxxxxxx 2,5 xxxxxxxxxx
Xxxxxxxxx xxxxxxxxxxxxxxxx xxxxxxxxxxxx 5 xxxxxxxxxx
Xxxxxxxxxxx 3 xxxxxxxxxx
Xxxxxxxx, xxxx 2 xx 3 5 xxxxxxxxxx
Xxxxx xxxxxxxxxxxxxxx (xxxxxxxxxxx)2
xxxxx 1 (Mahoney) 29 X xxxxxxxx xxxxxxxx3
xxxxx 2 (MEF1) 7 X xxxxxxxx antigenu3
typus 3 (Xxxxxxx) 26 X jednotek xxxxxxxx3
Xxxxxxxxxxx xx fosforečnan hlinitý 1,5 xx (0,33 xx Al3+)
1 Xxxx xxxxxx xxxxxxx xxxxxxxxx xxxxxxxxxxxxx (x = 0,95) xxxxxxxx xxxxxx xxxxx xxxxx xxxxxxxxx x Xxxxxxxxx xxxxxxxx
2 Xxxxxxxxxxx na Xxxx xxxxxxx
3 Xxxx xxxxxxxx xxxxxxxx xxxx úplně xxxxxx xxxx xx, xxxxx byla xxxxx xxxxxxxxx jako 40-8-32 X jednotek antigenu xxx virus xxxx 1, 2 a 3, xxx xxxxxx xxxxx xxxxxxx xxxxxxxxxxxxxx xxxxxxx
* Jako xxxxxx xxxxxxx xxxxxxxxx spolehlivosti (x = 0,95) xxxxxxxx xxxxxx podle xxxxx popsaného x Xxxxxxxxx xxxxxxxx
** Xxxxxxxxxxx xx Vero xxxxxxx.
1x) xxxxxxxx látka xxxxx xxxxxxxxxxx (XXX vakcína)
1k) xxxxxxxx xxxxx xxxxx xxxxxx xxxxxxxxxx X xxx xxxxx xxxxxxxx xx xxxxxxxxxxxx xxxxxxxx:
Xxxxx xxxxx (0,5 xx) xxxxxxx xxxxxxxx:
Xxxxxxxxx xxxxxxxxx xxxxxxxxxxx X1,2,3 - 20 mikrogramů
1 adjuvovaný xx AS04C obsahující: - 3-O-deacyl-4'-monofosforyl-lipid A (XXX)2 50 mikrogramů
2 xxxxxxxxxxx xx xxxxxxxxxxx xxxxxxx (xxxxxx 0,5 xxxxxxxxx Xx3+)
3 xxxxxxxx xx kultuře xxxxxxxxxxxx xxxxx (Xxxxxxxxxxxxx cerevisiae) xxxxxxxxxxxxx DNA xxxxxxxxxxx.
2. Xxxxxxxxx xxxxxxx xxxxxxxxxx xxxxx pro zvláštní xxxxxxxx
2x) xxxxxxxx xxxxx xxxxx virové xxxxxxxxxx X ve formuli xxx xxxxxxx:
Xxxxx xxxxx xxxxxxxx:
Xxxxxxxxx tegiminis xxxxxxxxxxx X - 20 xxxxxxxxxx
2x) očkovací látka xxxxx xxxxxxxxx
2x) xxxxxxxx xxxxx xxxxx xxxxxx xxxxxxxxxx A xx xxxxxxx pro xxxxxxx:
Xxxxx xxxxx obsahuje:
Hepatitis X xxxxx inactivatum
2d) xxxxxxxx xxxxx xxxxx xxxxxxxxxx, xxxxxxxxxx x xxxxxxxxx:
1 xxxxx rekonstituované xxxxxxx (0,5 xx) obsahuje:
Morbillorum xxxxx xxxxxxxxxx1 (Xxxxxxx) xxx. 103,0 xxxxxxxx xxxxx pro xxxxxxxx xxxxxxx503
Xxxxxxxxxxx xxxxx xxxxxxxxxx1 (XXX 4385) xxx. 103,7 xxxxxxxx xxxxx xxx buněčnou xxxxxxx503
Xxxxxxxx xxxxx xxxxxxxxxx2 (Xxxxxx XX 27/3) min. 103,0 infekční xxxxx xxx buněčnou xxxxxxx503
1 xxxxxxxxx xx xxxxxxx xxxxxxxx xxxxxx
2 pomnoženo xx xxxxxxxx xxxxxxxxxxx xxxxxxx (XXX-5)
3 50% xxxxxxxx xxxxx xxxxxxx xxxxxxx
XXXX
2xx) xxxxxxxx xxxxx xxxxx xxxxxxxxxx, xxxxxxxxxx x xxxxxxxxx
Xx rozpuštění xxxxxxxx xxxxx xxxxx (0,5 xx):
Xxxxx xxxxxxxxxxx1 xxxxx xxxxxxxxxx (xxxx Xxxxxx’ Xxxxxxxxx) xx xxxx xxx 1x103 XXXX50*
Xxxxx xxxxxxxxxxx1 xxxxx xxxxxxxxxx (xxxx Jeryl Xxxx™, hladina X) xx méně xxx 12,5x103 CCID50*
Virus rubeolae2 xxxxx attenuatum (xxxx Xxxxxx XX 27/3) xx xxxx xxx 1x103 XXXX50*
* 50% xxxxxxxx xxxxx xxxxxxx xxxxxxx
1 vyrobeno xx xxxxxxx xxxxxxxx embryí
2 xxxxxxxx xx xxxxxxxx xxxxxxxxxxx xxxxxxx XX-38 xxxxxxxxxxxxx.
3. Antigenní xxxxxxx xxxxxxxxxx xxxxx pro xxxxxxxxx xxxxxxxx
3x) xxxxxxxx xxxxx xxxxx xxxxxx xxxxxxxxxx X xx xxxxxxx xxx dospělé:
Virus xxxxxxxxx X xxxxxxxxxxx
3x) xxxxxxxx látka xxxxx xxxxxx hepatitidě X xx formuli xxx xxxx:
Xxxxx hepatitis X xxxxxxxxxxx
3x) xxxxxxxx xxxxx xxxxx xxxxxxxxxx, xxxxxxxxxx x xxxxxxxxx:
1 dávka xxxxxxxxxxxxxxx vakcíny (0,5 xx) obsahuje:
Morbillorum xxxxx xxxxxxxxxx1 (Xxxxxxx) xxx. 103,0 xxxxxxxx xxxxx xxx buněčnou xxxxxxx503
Xxxxxxxxxxx xxxxx xxxxxxxxxx1 (RIT 4385) min. 103,7 xxxxxxxx xxxxx pro xxxxxxxx kulturu503
Rubeolae xxxxx xxxxxxxxxx2 (Xxxxxx XX 27/3) xxx. 103,0 xxxxxxxx dávka xxx xxxxxxxx xxxxxxx503
1 xxxxxxxxx xx xxxxxxx kuřecích xxxxxx
2 xxxxxxxxx xx xxxxxxxx diploidních xxxxxxx (XXX-5)
3 50% xxxxxxxx xxxxx xxxxxxx xxxxxxx
XXXX
3xx) xxxxxxxx látka xxxxx xxxxxxxxxx, příušnicím a xxxxxxxxx
Xx rozpuštění xxxxxxxx xxxxx dávka (0,5 xx):
Xxxxx xxxxxxxxxxx1 xxxxx xxxxxxxxxx (kmen Xxxxxx’ Xxxxxxxxx) ne xxxx xxx 1x103 XXXX50*
Xxxxx xxxxxxxxxxx1 xxxxx xxxxxxxxxx (xxxx Jeryl Lynn™, xxxxxxx X) xx xxxx než 12,5x103 XXXX50*
Xxxxx rubeolae2 xxxxx xxxxxxxxxx (xxxx Xxxxxx XX 27/3) ne xxxx xxx 1x1103 XXXX50*
* 50% xxxxxxxx xxxxx xxxxxxx kultury
1 xxxxxxxx na xxxxxxx xxxxxxxx embryí
2 xxxxxxxx xx xxxxxxxx xxxxxxxxxxx xxxxxxxx WI-38 xxxxxxxxxxxxx.
&xxxx;
Xxxxxxx:
xxxx. XXXx. Válek, CSc., XXX, XXXX, v. x.
Xxxxxxxxx
Xxxxxx předpis č. 375/2024 Xx. xxxxx xxxxxxxxx xxxx 10.12.2024.
Xx xxx xxxxxxxx xxxxx xxxxx xx xxxxxxxxx.
Xxxxx xxxxxxxxxxxx xxxxxxxx xxxxx xxxxxx právních předpisů x odkazech xxxx xxxxxxxxxxxxx, xxxxx se xxxx netýká derogační xxxxx shora uvedeného xxxxxxxx předpisu.